HYBRID EVENT: You can participate in person at Boston, Massachusetts, USA or Virtually from your home or work.

4th Edition of Global Conference on

Addiction Medicine, Behavioral Health and Psychiatry

October 19-21, 2023 | Boston, Massachusetts, USA

GAB 2019

David J McCann

Speaker at Global Conference on Addiction Medicine and Behavioral Health 2019 - David J McCann
National Institute on Drug Abuse, United States
Title : Medications Development for the Treatment of Substance Use Disorders Recent Advances, Ongoing Projects, and Funding Opportunities


For almost 30 years, the U.S. National Institute on Drug Abuse (NIDA) has supported development of medications for the treatment of substance use disorders and their consequences.  Working in close partnership with the private sector and the U.S. Food and Drug Administration (FDA), NIDA supports related research efforts through a series of NIDA-directed contracts as well as through investigator-initiated grants.  Resulting FDA approvals to date include buprenorphine (Subutex) and buprenorphine/naloxone (Suboxone) SL tablets for the treatment of opioid use disorder (OUD), naltrexone (Vivitrol) monthly injection for the treatment of both OUD and alcohol use disorder, buprenorphine (Probuphine) implants for the treatment of OUD, naloxone nasal spray (nasal Narcan) for the treatment of opioid overdose, and lofexidine (Lucemyra) tablets for the treatment of opioid withdrawal.  Building on the success of the initial buprenorphine products, recent private sector research has resulted in regulatory approvals for a monthly buprenorphine injection product (Sublocade) in the U.S. and a set of weekly and monthly buprenorphine injection products (Buvidal) in the E.U. and Australia.  

 The current opioid overdose crisis in the U.S. has stimulated new research to increase treatment options for OUD and opioid overdose patients, and to develop safer and/or less addictive analgesics.  In addition, substantial resources are being directed toward the development of medications to treat stimulant (cocaine and methamphetamine) use disorders.  Small drug molecules as well as immunologic (vaccine and monoclonal antibody) products are under evaluation.

Multiple funding opportunities are available for future medication development efforts.  Researchers in the private sector as well as academia are eligible to apply for grants.  In addition, NIDA has established a contract infrastructure the can facilitate the development of high priority compounds.


Dr. McCann is Associate Director of the Division of Therapeutics and Medical Consequences at NIDA.  He received a B.S. in Pharmacy (1981) from the Albany College of Pharmacy and his Ph.D. (1988) from the Department of Pharmacology and Experimental Therapeutics at the State University of New York at Buffalo.  He conducted his postdoctoral research at the NIDA Intramural Research Program in Baltimore, MD.  In his current position, his primary responsibility is to facilitate the discovery and development of medications to treat substance use disorders through oversight of the Division’s contract program and by establishing NIDA/private sector collaborations.