Positive outcome of adherence to the reward deficiency syndrome solution system treatment plan: A longitudinal study

Title : Positive outcome of adherence to the reward deficiency syndrome solution system treatment plan: A longitudinal study

Abstract:

The purpose of this editorial is to update the progress of Elle foundation case study 101, for whom a reward deficiency syndrome solution system (RDSSS) treatment plan was created in 2020, and her progress tracked daily during phase one in 2021. Analysis of phase one of this longitudinal study has been reported in more than one journal submission and published in peer review However, we have not yet reported the results of phase 2 or 3 in peer review.

The case study’s daily progress during each phase is tracked for 9 months, with three months off in between phases. Phase two was observed in year 2 of the study, which was 2022. Phase 3 was observed in year 3, 2023. Phase four is currently in progress, in 2024. In review, the RDS treatment plan developed by Blum’s group which was created for this participant began with genetic addiction risk severity (GARS) Screening. Test results found: 1) one risk allele (C/T), in the single nucleotide polymorphism DRD4; 2) 2 risk alleles in the variable tandem number repeats and insertions/deletions of the 5-HTT-Linked gene (S/S); and 3) risk alleles (4R/4R) of the variable tandem number repeats of MAOA 

The following tracks her remarkable progress in physiological, neurological, psychological social, and spiritual realms, attesting to the Reward Deficiency Syndrome Solution System, and the impact this has on individuals with complex mental disorders clusters.

Biography:

Elizabeth Dale Gilley is a research scientist who focuses upon underlying neurogenetic and neurobiological syndrome which manifest as Substance Use Disorders and comorbid Mental Health Disorder Clusters.  The Elle Foundation 100 series in family genomics clearly demonstrates the Reward Deficiency Syndrome paradigm and how genomic applications  benefit RDS families over the generations. She is in her 6^th year of longitudinal studies for the 100s series.  She is in the data collection analysis phase of the 200s series, which will inform the design of a much larger study known as the EF300s.