7th Edition of Global Conference on
Addiction Medicine, Behavioral Health and Psychiatry
October 19-21, 2026 | Boston, Massachusetts, USA
Cross-Tolerance in Substance Use
Cross-tolerance occurs when the use of one substance reduces sensitivity to another, often due to overlapping mechanisms of action. For example, tolerance to alcohol may result in reduced responsiveness to benzodiazepines, as both affect the GABAergic system. This phenomenon complicates treatment and increases the risk of overdose when individuals switch or combine substances to achieve the desired effect. Cross-tolerance is a significant challenge in managing polysubstance use disorders, as it may necessitate higher doses of medications for effective treatment, increasing potential side effects. Treatment strategies include careful assessment of cross-tolerance patterns, gradual tapering protocols, and alternative medications that bypass tolerance mechanisms. Recognizing cross-tolerance is critical in designing safer and more effective addiction management plans.
Nile Stanley
University of North Florida, United States
Ann Marie Leonard Zabel
Curry College, United States
Edie Raether
NeuroShifts and Wings for Wishes Academy, United States
John Michael Weber
Open Door Mission in Houston Texas, United States
Owonaro Peter
Bayelsa State Drug Avuse Addiction Prevention and Rehabilitation Committee (BADAPARC), Nigeria
Sindu Padmanabhan
Bharathiar University, India
Andrew Drasen
A Vision of Hope Media, United StatesSubmit your abstract Today
Title : Integrating bibliopoetry therapy and digital health technologies for inflammation management: A neuropsychosomatic perspective
Nile Stanley, University of North Florida, United States
Title : Evaluation of prevalence and pattern of tobacco use in yenagoa city in bayelsa state south of nigeria
Owonaro Peter, Bayelsa State Drug Avuse Addiction Prevention and Rehabilitation Committee (BADAPARC), Nigeria
Title : Engaging learners through gamification, creativity, and human-centered design
Tero Moliis, Versantium, United States
Title : Neuropharmacological and regulatory drivers of tianeptine misuse in the united states: A growing public health concern
Darcy Tocci, NSU College of Pharmacy, United States
Title : Awakening sovereignty within: Healing trauma, releasing codependency, and returning to self-trust
Whitney Walker, Mental Health Therapist/ Podcast Host, United States
Title : You can save a life: Real conversations, real solutions for suicide prevention
frank King, The Mental Health Comedian, LLC, United States