7th Edition of Global Conference on
Addiction Medicine, Behavioral Health and Psychiatry
October 19-21, 2026 | Boston, Massachusetts, USA
Cross-Tolerance in Substance Use
Cross-tolerance occurs when the use of one substance reduces sensitivity to another, often due to overlapping mechanisms of action. For example, tolerance to alcohol may result in reduced responsiveness to benzodiazepines, as both affect the GABAergic system. This phenomenon complicates treatment and increases the risk of overdose when individuals switch or combine substances to achieve the desired effect. Cross-tolerance is a significant challenge in managing polysubstance use disorders, as it may necessitate higher doses of medications for effective treatment, increasing potential side effects. Treatment strategies include careful assessment of cross-tolerance patterns, gradual tapering protocols, and alternative medications that bypass tolerance mechanisms. Recognizing cross-tolerance is critical in designing safer and more effective addiction management plans.
Nile Stanley
University of North Florida, United States
Ann Marie Leonard Zabel
Curry College, United States
Edie Raether
NeuroShifts and Wings for Wishes Academy, United States
Sindu Padmanabhan
Bharathiar University, India
Kayla Albers
Hazelden Betty Ford Graduate School, United States
Jorja Jamison
Hazelden Betty Ford Graduate School, United States
Andrew Drasen
A Vision of Hope Media, United StatesSubmit your abstract Today
Title : Integrating bibliopoetry therapy and digital health technologies for inflammation management: A neuropsychosomatic perspective
Nile Stanley, University of North Florida, United States
Title : The Storm Within: Neuropsychological Insights into Dysregulation and Substance Use in the Adolescent Brain.
Ann Marie Leonard Zabel, Curry College, United States
Title : Sexualizing anxiety and anxiolytic sex: Misattribution of arousal
Sam Vaknin, CIAPS, Cambridge, United Kingdom
Title : Creative exploration of the complexity of the pre-lapse experience in the addict to add retrospective insight
Eric A Kreuter, Cornerstone of Rhinebeck, United States
Title : Resilience in counseling: Processing grief for the addictions counselor
Jorja Jamison, Hazelden Betty Ford Graduate School, United States
Title : Resilience in counseling: Processing grief for the addictions counselor
Kayla Albers, Hazelden Betty Ford Graduate School, United States