7th Edition of Global Conference on
Addiction Medicine, Behavioral Health and Psychiatry
October 19-21, 2026 | Boston, Massachusetts, USA
Cross-Tolerance in Substance Use
Cross-tolerance occurs when the use of one substance reduces sensitivity to another, often due to overlapping mechanisms of action. For example, tolerance to alcohol may result in reduced responsiveness to benzodiazepines, as both affect the GABAergic system. This phenomenon complicates treatment and increases the risk of overdose when individuals switch or combine substances to achieve the desired effect. Cross-tolerance is a significant challenge in managing polysubstance use disorders, as it may necessitate higher doses of medications for effective treatment, increasing potential side effects. Treatment strategies include careful assessment of cross-tolerance patterns, gradual tapering protocols, and alternative medications that bypass tolerance mechanisms. Recognizing cross-tolerance is critical in designing safer and more effective addiction management plans.
John Michael Weber
Open Door Mission in Houston Texas, United States
Frederick J Goldstein
Philadelphia College of Osteopathic Medicine, United States
Nile Stanley
University of North Florida, United States
Andrew Drasen
A Vision of Hope Media, United States
Eric Cohen
Livio Labs, United States
John Michael Weber
Open Door Mission in Houston Texas, United States
Denis Larrivee
University of Navarra, SpainSubmit your abstract Today
Title : Integrating bibliopoetry therapy and digital health technologies for inflammation management: A neuropsychosomatic perspective
Nile Stanley, University of North Florida, United States
Title : Reduction of chronic neuropathic pain by a THC-CBD combination capsule: ongoing pilot study
Frederick J Goldstein, Philadelphia College of Osteopathic Medicine, United States
Title : Suicide prevention strategies for the law enforcement profession
Stephanie Schweitzer Dixon, SSD Consulting, United States
Title : The twelve steps beyond alcohol: Applying recovery principles to food, perfectionism, and modern behavioral addictions
Mary Dobson, Liftwell Health, United States
Title : Understanding polyvagal dysregulation, addiction, and relationships: A holistic framework for mental health and recovery
Kimberly Lannon, Your Daily Game Face, United States
Title : Kratom: Exploring its pharmacology, mental health effects, and new challenges for addiction and behavioral health experts
Kimberly Lannon, Your Daily Game Face, United States