Decision-making impairments are hallmark symptoms of substance use disorders, resulting from dysregulation in brain regions like the prefrontal cortex and amygdala. Chronic substance use alters neural circuits, reducing the ability to weigh long-term consequences and increasing impulsivity. This leads to a cycle of poor choices, including continued drug use despite adverse outcomes. Behavioral therapies such as CBT aim to improve decision-making skills by fostering self-awareness and promoting healthier coping mechanisms. Understanding these impairments helps tailor interventions to restore cognitive functions and support sustainable recovery in individuals with substance use disorders.
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Nile Stanley, University of North Florida, United States
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Frederick J Goldstein, Philadelphia College of Osteopathic Medicine, United States
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