Endocrine Dysregulation in Addiction

Substance use significantly impacts the endocrine system, disrupting hormonal balances essential for body functions. For example, chronic alcohol consumption can impair the hypothalamic-pituitary-adrenal (HPA) axis, leading to cortisol imbalances that affect stress responses. Opioid use often reduces testosterone levels, causing fatigue and mood disturbances. Endocrine dysregulation contributes to both the physical and psychological challenges in addiction recovery. Hormonal assessments and targeted treatments, such as hormone replacement therapy, can help mitigate these effects. Combining endocrine care with addiction treatment supports holistic recovery and long-term health improvement.