HYBRID EVENT: You can participate in person at Boston, Massachusetts, USA or Virtually from your home or work.

7th Edition of Global Conference on

Addiction Medicine, Behavioral Health and Psychiatry

October 19-21, 2026 | Boston, Massachusetts, USA

Endorphin System in Addiction

Endorphin System in Addiction

The endorphin system plays a vital role in regulating mood, pain, and emotional responses, and it is closely linked to the development of addiction. Endorphins are natural chemicals produced by the brain that interact with opioid receptors, helping to relieve pain and create feelings of well-being or euphoria. Addictive substances, such as alcohol, heroin, and other opioids, can artificially boost the release of endorphins, leading to intense pleasure and reinforcing the desire to continue using the substance. Over time, the brain becomes dependent on these external sources of endorphins, which can contribute to physical dependence and addiction. Understanding the endorphin system has led to treatments that target its function, including medications like naltrexone, which blocks opioid receptors and helps reduce cravings, aiding in long-term recovery from addiction.

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