6th Edition of Global Conference on
Addiction Medicine, Behavioral Health and Psychiatry
October 20-22, 2025 | Orlando, Florida, USA
Neural Circuits in Substance Dependence
Substance dependence alters neural circuits involved in reward, motivation, and self-control. The mesolimbic pathway, involving the ventral tegmental area (VTA) and nucleus accumbens, becomes hyperactive, reinforcing drug-seeking behaviors. The prefrontal cortex, which regulates impulse control, often shows reduced activity, leading to impaired decision-making. Chronic substance use also affects the stress-response system, mediated by the hypothalamus and amygdala, perpetuating cycles of craving and relapse. Advances in neuroimaging have illuminated these disruptions, paving the way for innovative treatments like deep brain stimulation (DBS) and neurofeedback. Understanding these circuits is key to developing targeted therapies for addiction.
Nile Stanley
University of North Florida, United States
Ann Marie Leonard Zabel
Curry College, United States
Denis Larrivee
University of Navarra, Spain
Scharbach Hugues
Paris University, France
Alphonsus Obayuwana
Triple-H Project LLC, United States
Malasri Chaudhery Malgeri
Recovery com, United States
Jana Furstova
Palacký University Olomouc, Czech RepublicSubmit your abstract Today
Title : Tailoring biblio-poetry therapies using AI and biofeedback for addiction treatment
Nile Stanley, University of North Florida, United States
Title : The A-B-C of happiness coaching
Alphonsus Obayuwana, Triple-H Project LLC, United States
Title : Clinical pharmacology of marijuana: Update 2024
Frederick J Goldstein, Philadelphia College of Osteopathic Medicine, United States
Title : Trait-based recovery: Evidence-based trait activation to reduce depression, anxiety, and improve client engagement in addiction treatment
Jason Glenn Roop, The Center for Trait-Based Transformation, United States
Title : An investigation of the factors responsible for ubstance abuse from a cognitive perspective based on a mixed method approach
Adewole Olukorede, Literary Edifice, Italy
Title : A Long-Acting Naltrexone Implant (for Opioid Use Disorder: First-in-Human Phase I Trial)
Steven M Cohen, Akyso Therapeutics, United States