HYBRID EVENT: Join us in person in Boston, Massachusetts, USA or attend virtually from anywhere.

7th Edition of Global Conference on

Addiction Medicine, Behavioral Health and Psychiatry

October 19-21, 2026 | Boston, Massachusetts, USA

Neural Circuits in Substance Dependence

Neural Circuits in Substance Dependence

Substance dependence alters neural circuits involved in reward, motivation, and self-control. The mesolimbic pathway, involving the ventral tegmental area (VTA) and nucleus accumbens, becomes hyperactive, reinforcing drug-seeking behaviors. The prefrontal cortex, which regulates impulse control, often shows reduced activity, leading to impaired decision-making. Chronic substance use also affects the stress-response system, mediated by the hypothalamus and amygdala, perpetuating cycles of craving and relapse. Advances in neuroimaging have illuminated these disruptions, paving the way for innovative treatments like deep brain stimulation (DBS) and neurofeedback. Understanding these circuits is key to developing targeted therapies for addiction.

Committee Members
Speaker at Addiction Medicine, Behavioral Health and Psychiatry 2026 - John Michael Weber

John Michael Weber

Open Door Mission in Houston Texas, United States
Speaker at Addiction Medicine, Behavioral Health and Psychiatry 2026 - Frederick J Goldstein

Frederick J Goldstein

Philadelphia College of Osteopathic Medicine, United States
Speaker at Addiction Medicine, Behavioral Health and Psychiatry 2026 - Nile Stanley

Nile Stanley

University of North Florida, United States
GAB 2026 Speakers
Speaker at Addiction Medicine, Behavioral Health and Psychiatry 2026 - Andrew Drasen

Andrew Drasen

A Vision of Hope Media, United States
Speaker at Addiction Medicine, Behavioral Health and Psychiatry 2026 - Eric Cohen

Eric Cohen

Livio Labs, United States
Speaker at Addiction Medicine, Behavioral Health and Psychiatry 2026 - John Michael Weber

John Michael Weber

Open Door Mission in Houston Texas, United States
Speaker at Addiction Medicine, Behavioral Health and Psychiatry 2026 - Denis Larrivee

Denis Larrivee

University of Navarra, Spain
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