6th Edition of Global Conference on
Addiction Medicine, Behavioral Health and Psychiatry
October 20-22, 2025 | Orlando, Florida, USA
Neural Circuits in Substance Dependence
Substance dependence alters neural circuits involved in reward, motivation, and self-control. The mesolimbic pathway, involving the ventral tegmental area (VTA) and nucleus accumbens, becomes hyperactive, reinforcing drug-seeking behaviors. The prefrontal cortex, which regulates impulse control, often shows reduced activity, leading to impaired decision-making. Chronic substance use also affects the stress-response system, mediated by the hypothalamus and amygdala, perpetuating cycles of craving and relapse. Advances in neuroimaging have illuminated these disruptions, paving the way for innovative treatments like deep brain stimulation (DBS) and neurofeedback. Understanding these circuits is key to developing targeted therapies for addiction.
Nile Stanley
University of North Florida, United States
Ann Marie Leonard Zabel
Curry College, United States
Denis Larrivee
University of Navarra, Spain
Scharbach Hugues
Paris University, France
Alphonsus Obayuwana
Triple-H Project LLC, United States
Michelle Charbonnier
MoNetwork, United States
Monica Zuniga Fajuri
Tiburcio Vasquez Health Center, United StatesSubmit your abstract Today
Title : Tailoring biblio-poetry therapies using AI and biofeedback for addiction treatment
Nile Stanley, University of North Florida, United States
Title : Clinical pharmacology of marijuana: Update 2024
Frederick J Goldstein, Philadelphia College of Osteopathic Medicine, United States
Title : Gangstalking is real, should be studied
Sam Vaknin, Southern Federal University, United Kingdom
Title : Decoding aggression, violence, and substance use in adolescents with conduct disorders: Neurochemical pathways and interventions
Ann Marie Leonard Zabel, Curry College, United States
Title : Sensoria driven genetic decoupling and impaired areal integration in diseases of agency
Denis Larrivee, University of Navarra, Spain
Title : Positive outcome of adherence to the reward deficiency syndrome solution system treatment plan: A longitudinal study
Elizabeth Dale Gilley, The Elle Foundation, United States