7th Edition of Global Conference on
Addiction Medicine, Behavioral Health and Psychiatry
October 19-21, 2026 | Boston, Massachusetts, USA
Neural Circuits in Substance Dependence
Substance dependence alters neural circuits involved in reward, motivation, and self-control. The mesolimbic pathway, involving the ventral tegmental area (VTA) and nucleus accumbens, becomes hyperactive, reinforcing drug-seeking behaviors. The prefrontal cortex, which regulates impulse control, often shows reduced activity, leading to impaired decision-making. Chronic substance use also affects the stress-response system, mediated by the hypothalamus and amygdala, perpetuating cycles of craving and relapse. Advances in neuroimaging have illuminated these disruptions, paving the way for innovative treatments like deep brain stimulation (DBS) and neurofeedback. Understanding these circuits is key to developing targeted therapies for addiction.
John Michael Weber
Trauma Healed Life Coach, United States
Frederick J Goldstein
Philadelphia College of Osteopathic Medicine, United States
Nile Stanley
University of North Florida, United States
Andrew Drasen
A Vision of Hope Media, United States
John Michael Weber
Trauma Healed Life Coach, United States
Denis Larrivee
University of Navarra, Spain
Sam Vaknin
CIAPS, Cambridge, United KingdomSubmit your abstract Today
Title : Integrating bibliopoetry therapy and digital health technologies for inflammation management: A neuropsychosomatic perspective
Nile Stanley, University of North Florida, United States
Title : PIVOT: Predictive intervention for vaping using resonance modeling of oscillatory, psychological, and trigger dynamics
Aadya, Issaquah High School, United States
Title : The storm within: Neuropsychological insights into dysregulation and substance use in the adolescent brain
Ann Marie Leonard Zabel, Curry College, United States
Title : Addiction and the failure of meaning-forming
Jenni Guentcheva, GTI, United States
Title : What to do when a tragedy strikes
Alphonsus Obayuwana, Triple-H Project LLC, United States
Title : Reward deficiency syndrome solution patient claims ‘dopamine homeostasis’ provided the neurological stability to begin focusing upon healing psychic fracture associated with chronic post-traumatic stress disorder dissociative multiplicity
Elizabeth Dale Gilley, The Elle Foundation, United States