Substance use disorders (SUDs) are closely linked to neurochemical imbalances in the brain. Drugs and alcohol disrupt normal neurotransmitter activity, particularly dopamine, serotonin, and glutamate systems. This dysregulation contributes to cravings, withdrawal symptoms, and compulsive substance-seeking behaviors. Chronic use alters brain reward pathways, making natural rewards less satisfying and perpetuating addiction cycles. Addressing these imbalances often requires a combination of pharmacotherapy, such as medications that stabilize neurotransmitter levels, and behavioral interventions like CBT. Understanding the neurochemical underpinnings of SUDs enables clinicians to tailor treatments, improving recovery outcomes and reducing relapse risks.
Title : The storm within: Neuropsychological insights into dysregulation and substance use in the adolescent brain
Ann Marie Leonard Zabel, Curry College and NEALAC Clinic , United States
Title : The effect of Balint training on self-efficacy and empathy among medical students and the moderator role of personality traits and choice of specialty
Meni Koslowsky, Ariel University, Israel
Title : Sexualizing anxiety and anxiolytic sex: Misattribution of arousal
Sam Vaknin, Commonwealth Institute of Advanced Professional Studies, United Kingdom
Title : Dr Jekyll and Mr. Hyde revealed: Tales from the default mode network
Christopher Ashton, TeDDs on Chapel, Centre for Recovery, Canada
Title : Integrating bibliopoetry therapy and digital health technologies for inflammation management: A neuropsychosomatic perspective
Nile Stanley, University of North Florida, United States
Title : Addiction and the failure of meaning-forming
Jenni Guentcheva, GoodNeighbor LLC, United States