6th Edition of Global Conference on
Addiction Medicine, Behavioral Health and Psychiatry
October 20-22, 2025 | Orlando, Florida, USA
Neuropharmacology of Relapse in Substance Dependence
Relapse is a common and complex challenge in substance dependence, driven by alterations in the brain's reward and stress systems. Chronic substance use dysregulates neurotransmitters like dopamine, glutamate, and GABA, leading to cravings and reduced impulse control. Neuroplastic changes in the prefrontal cortex impair decision-making, while the amygdala's heightened sensitivity increases emotional triggers. Stress and environmental cues often act as catalysts for relapse. Pharmacological interventions such as naltrexone, buprenorphine, and anti-craving agents target these mechanisms to prevent relapse. Understanding the neurobiological underpinnings enables the development of personalized treatment plans, combining medication with behavioral therapies to address the root causes and promote long-term abstinence.
Nile Stanley
University of North Florida, United States
Ann Marie Leonard Zabel
Curry College, United States
Denis Larrivee
University of Navarra, Spain
Scharbach Hugues
Paris University, France
Alphonsus Obayuwana
Triple-H Project LLC, United States
Jana Furstova
Palacký University Olomouc, Czech Republic
Alexander Kharibegashvil
Telavi State University, GeorgiaSubmit your abstract Today
Title : Decoding aggression, violence, and substance use in adolescents with conduct disorders: Neurochemical pathways and interventions
Ann Marie Leonard Zabel, Curry College, United States
Title : Integrative addiction and mental health wellness lecture
John Giordano, Life Enhancement Recovery Center, United States
Title : Step one therapy
Ashton Christopher, Center for Recovery, Canada
Title : Addiction rehabilitation & recovery: Pathways to healing and resilience
Sindu Padmanabhan, Bharathiar University, India
Title : Tailoring biblio-poetry therapies using AI and biofeedback for addiction treatment
Nile Stanley, University of North Florida, United States
Title : The A-B-C of happiness coaching
Alphonsus Obayuwana, Triple-H Project LLC, United States