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7th Edition of Global Conference on

Addiction Medicine, Behavioral Health and Psychiatry

October 19-21, 2026 | Boston, Massachusetts, USA

Neuropharmacology of Relapse in Substance Dependence

Neuropharmacology of Relapse in Substance Dependence

Relapse is a common and complex challenge in substance dependence, driven by alterations in the brain's reward and stress systems. Chronic substance use dysregulates neurotransmitters like dopamine, glutamate, and GABA, leading to cravings and reduced impulse control. Neuroplastic changes in the prefrontal cortex impair decision-making, while the amygdala's heightened sensitivity increases emotional triggers. Stress and environmental cues often act as catalysts for relapse. Pharmacological interventions such as naltrexone, buprenorphine, and anti-craving agents target these mechanisms to prevent relapse. Understanding the neurobiological underpinnings enables the development of personalized treatment plans, combining medication with behavioral therapies to address the root causes and promote long-term abstinence.

Committee Members
Speaker at Addiction Medicine, Behavioral Health and Psychiatry 2026 - John Michael Weber

John Michael Weber

Open Door Mission in Houston Texas, United States
Speaker at Addiction Medicine, Behavioral Health and Psychiatry 2026 - Frederick J Goldstein

Frederick J Goldstein

Philadelphia College of Osteopathic Medicine, United States
Speaker at Addiction Medicine, Behavioral Health and Psychiatry 2026 - Nile Stanley

Nile Stanley

University of North Florida, United States
GAB 2026 Speakers
Speaker at Addiction Medicine, Behavioral Health and Psychiatry 2026 - Andrew Drasen

Andrew Drasen

A Vision of Hope Media, United States
Speaker at Addiction Medicine, Behavioral Health and Psychiatry 2026 - Eric Cohen

Eric Cohen

Livio Labs, United States
Speaker at Addiction Medicine, Behavioral Health and Psychiatry 2026 - John Michael Weber

John Michael Weber

Open Door Mission in Houston Texas, United States
Speaker at Addiction Medicine, Behavioral Health and Psychiatry 2026 - Denis Larrivee

Denis Larrivee

University of Navarra, Spain
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