7th Edition of Global Conference on
Addiction Medicine, Behavioral Health and Psychiatry
October 19-21, 2026 | Boston, Massachusetts, USA
Neuropharmacology of Relapse in Substance Dependence
Relapse is a common and complex challenge in substance dependence, driven by alterations in the brain's reward and stress systems. Chronic substance use dysregulates neurotransmitters like dopamine, glutamate, and GABA, leading to cravings and reduced impulse control. Neuroplastic changes in the prefrontal cortex impair decision-making, while the amygdala's heightened sensitivity increases emotional triggers. Stress and environmental cues often act as catalysts for relapse. Pharmacological interventions such as naltrexone, buprenorphine, and anti-craving agents target these mechanisms to prevent relapse. Understanding the neurobiological underpinnings enables the development of personalized treatment plans, combining medication with behavioral therapies to address the root causes and promote long-term abstinence.
Frederick J Goldstein
Philadelphia College of Osteopathic Medicine, United States
Nile Stanley
University of North Florida, United States
Ann Marie Leonard Zabel
Curry College and NEALAC Clinic , United States
John Michael Weber
Trauma Healed Life Coach, United States
Denis Larrivee
University of Navarra, Spain
Steve Cohen
Medvesta Hypnosis Healthcare, United States
Andrew Drasen
A Vision of Hope Media, United StatesSubmit your abstract Today
Title : The storm within: Neuropsychological insights into dysregulation and substance use in the adolescent brain
Ann Marie Leonard Zabel, Curry College and NEALAC Clinic , United States
Title : What to do when a tragedy strikes
Alphonsus Obayuwana, Triple-H Project LLC, United States
Title : The effect of Balint training on self-efficacy and empathy among medical students and the moderator role of personality traits and choice of specialty
Meni Koslowsky, Ariel University, Israel
Title : Genetic decoupling and global regulatory failure in diseases of agency
Denis Larrivee, University of Navarra, Spain
Title : Dr Jekyll and Mr. Hyde revealed: Tales from the default mode network
Christopher Ashton, TeDDs on Chapel, Centre for Recovery, Canada
Title : An unusual perspective for understanding and preventing bulimia relapse: Unhealthy sibling loyalty
Karen Gail Lewis, Private Practice, United States