Cocaine addiction presents a significant challenge in treatment, as there are currently no FDA-approved medications specifically for its management. However, various pharmacotherapies are being explored to mitigate cravings and reduce relapse rates. Medications such as antidepressants, dopamine agonists, and anti-anxiety drugs can be used to treat the underlying neurochemical imbalances associated with cocaine addiction. Behavioral therapies, such as cognitive-behavioral therapy (CBT), are often integrated with pharmacological interventions to address the psychological components of addiction. Combining pharmacotherapy with psychosocial treatments has shown promise in improving long-term recovery outcomes for individuals with cocaine addiction.