Substance use disorders (SUDs) fundamentally alter the brain's reward system, which is primarily governed by dopamine. Drugs hijack this system, providing exaggerated rewards that surpass natural stimuli, such as food or social interaction. Over time, this leads to diminished sensitivity, making ordinary pleasures less rewarding. The imbalance in reward processing perpetuates compulsive drug-seeking behaviors. Neuroimaging studies reveal significant changes in brain regions like the nucleus accumbens and prefrontal cortex, which regulate motivation and decision-making. Treatment approaches aim to recalibrate the reward system through behavioral therapies and medications, promoting the restoration of normal functioning.
Title : The storm within: Neuropsychological insights into dysregulation and substance use in the adolescent brain
Ann Marie Leonard Zabel, Curry College, United States
Title : Integrating bibliopoetry therapy and digital health technologies for inflammation management: A neuropsychosomatic perspective
Nile Stanley, University of North Florida, United States
Title : Trauma: Till death do us part
John Michael Weber, Trauma Healed Life Coach, United States
Title : Power, the underlying psychosocial factor in sexual trauma
Maryam Hazeghazam, Jesse Brown VA MC, United States
Title : Beyond abstinence: Understanding the shape of compulsive substance use, recovery and relapse
Antonio M Ocana, Epiphany360.io, Spain
Title : Medication assisted treatment for opioid use disorder: Successes, failures, and the precision psychiatry model in opioid use disorder care
Obianuju M Akujuobi, Rochester Regional Health, United States