Substance use disorders (SUDs) fundamentally alter the brain's reward system, which is primarily governed by dopamine. Drugs hijack this system, providing exaggerated rewards that surpass natural stimuli, such as food or social interaction. Over time, this leads to diminished sensitivity, making ordinary pleasures less rewarding. The imbalance in reward processing perpetuates compulsive drug-seeking behaviors. Neuroimaging studies reveal significant changes in brain regions like the nucleus accumbens and prefrontal cortex, which regulate motivation and decision-making. Treatment approaches aim to recalibrate the reward system through behavioral therapies and medications, promoting the restoration of normal functioning.
Title : Tailoring biblio-poetry therapies using AI and biofeedback for addiction treatment
Nile Stanley, University of North Florida, United States
Title : The A-B-C of happiness coaching
Alphonsus Obayuwana, Triple-H Project LLC, United States
Title : Clinical pharmacology of marijuana: Update 2024
Frederick J Goldstein, Philadelphia College of Osteopathic Medicine, United States
Title : Trait-based recovery: Evidence-based trait activation to reduce depression, anxiety, and improve client engagement in addiction treatment
Jason Glenn Roop, The Center for Trait-Based Transformation, United States
Title : An investigation of the factors responsible for ubstance abuse from a cognitive perspective based on a mixed method approach
Adewole Olukorede, Literary Edifice, Italy
Title : A Long-Acting Naltrexone Implant (for Opioid Use Disorder: First-in-Human Phase I Trial)
Steven M Cohen, Akyso Therapeutics, United States