Long-term substance use can lead to noticeable shifts in personality traits, often characterized by increased irritability, impulsiveness, and emotional instability. These changes occur as addictive substances alter brain regions responsible for regulating emotions and social behavior, such as the prefrontal cortex and limbic system. For instance, individuals may display heightened aggression, reduced patience, or detachment from personal relationships. These personality changes can hinder recovery efforts and strain social connections, making holistic intervention critical. Therapeutic approaches, such as cognitive-behavioral therapy (CBT) and mindfulness-based practices, focus on rebuilding emotional resilience and fostering self-control. Addressing these behavioral shifts not only aids in recovery but also helps individuals rebuild trust and healthy relationships.