Managing withdrawal syndrome is a crucial aspect of addiction treatment, as withdrawal symptoms can be both physically and psychologically intense. The severity of withdrawal depends on the substance involved, the duration of use, and the individual's physical health. Symptoms can range from mild discomfort, such as irritability and fatigue, to severe effects like seizures, hallucinations, or even life-threatening complications. Medical detoxification is often the first step in managing withdrawal, involving a controlled environment where healthcare providers can monitor and treat symptoms as they arise. Medications, such as benzodiazepines for alcohol withdrawal or opioid agonists for opioid withdrawal, may be used to alleviate symptoms and reduce the risk of relapse. After detox, long-term treatment focuses on maintaining sobriety through therapy and support.