Drug craving is a key feature of addiction, driven by complex neural mechanisms involving reward and memory circuits. The mesolimbic dopamine pathway, particularly the nucleus accumbens, plays a central role in craving by reinforcing substance-related cues. The prefrontal cortex, responsible for decision-making and impulse control, often exhibits impaired functioning, making it difficult for individuals to resist urges. Additionally, the amygdala and hippocampus contribute by linking emotional and contextual triggers to past substance use experiences. Neuroimaging studies have revealed heightened activity in these brain regions during craving episodes, highlighting potential targets for interventions like transcranial magnetic stimulation (TMS) and pharmacotherapy to reduce craving intensity.
Title : The storm within: Neuropsychological insights into dysregulation and substance use in the adolescent brain
Ann Marie Leonard Zabel, Curry College and NEALAC Clinic , United States
Title : The effect of Balint training on self-efficacy and empathy among medical students and the moderator role of personality traits and choice of specialty
Meni Koslowsky, Ariel University, Israel
Title : Sexualizing anxiety and anxiolytic sex: Misattribution of arousal
Sam Vaknin, Commonwealth Institute of Advanced Professional Studies, United Kingdom
Title : Dr Jekyll and Mr. Hyde revealed: Tales from the default mode network
Christopher Ashton, TeDDs on Chapel, Centre for Recovery, Canada
Title : Integrating bibliopoetry therapy and digital health technologies for inflammation management: A neuropsychosomatic perspective
Nile Stanley, University of North Florida, United States
Title : Addiction and the failure of meaning-forming
Jenni Guentcheva, GoodNeighbor LLC, United States