Drug craving is a key feature of addiction, driven by complex neural mechanisms involving reward and memory circuits. The mesolimbic dopamine pathway, particularly the nucleus accumbens, plays a central role in craving by reinforcing substance-related cues. The prefrontal cortex, responsible for decision-making and impulse control, often exhibits impaired functioning, making it difficult for individuals to resist urges. Additionally, the amygdala and hippocampus contribute by linking emotional and contextual triggers to past substance use experiences. Neuroimaging studies have revealed heightened activity in these brain regions during craving episodes, highlighting potential targets for interventions like transcranial magnetic stimulation (TMS) and pharmacotherapy to reduce craving intensity.
Title : The storm within: Neuropsychological insights into dysregulation and substance use in the adolescent brain
Ann Marie Leonard Zabel, Curry College and NEALAC Clinic , United States
Title : What to do when a tragedy strikes
Alphonsus Obayuwana, Triple-H Project LLC, United States
Title : The effect of Balint training on self-efficacy and empathy among medical students and the moderator role of personality traits and choice of specialty
Meni Koslowsky, Ariel University, Israel
Title : Genetic decoupling and global regulatory failure in diseases of agency
Denis Larrivee, University of Navarra, Spain
Title : Dr Jekyll and Mr. Hyde revealed: Tales from the default mode network
Christopher Ashton, TeDDs on Chapel, Centre for Recovery, Canada
Title : An unusual perspective for understanding and preventing bulimia relapse: Unhealthy sibling loyalty
Karen Gail Lewis, Private Practice, United States