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7th Edition of Global Conference on

Addiction Medicine, Behavioral Health and Psychiatry

October 19-21, 2026 | Boston, Massachusetts, USA

Neuroanatomy of Substance Dependence

Neuroanatomy of Substance Dependence

Substance dependence is deeply rooted in the brain's neuroanatomy, particularly involving the reward system, which includes the nucleus accumbens, prefrontal cortex, and ventral tegmental area. These structures regulate pleasure, motivation, and impulse control. Drugs like cocaine, opioids, and alcohol hijack this system by artificially increasing dopamine levels, reinforcing addictive behaviors. Over time, chronic use leads to structural and functional changes, such as reduced gray matter in the prefrontal cortex, impairing decision-making and self-regulation. Neuroplasticity plays a dual role in dependence and recovery, with targeted therapies focusing on rewiring these neural circuits to restore normal functioning.

Committee Members
Speaker at Addiction Medicine, Behavioral Health and Psychiatry 2026 - John Michael Weber

John Michael Weber

Open Door Mission in Houston Texas, United States
Speaker at Addiction Medicine, Behavioral Health and Psychiatry 2026 - Frederick J Goldstein

Frederick J Goldstein

Philadelphia College of Osteopathic Medicine, United States
Speaker at Addiction Medicine, Behavioral Health and Psychiatry 2026 - Nile Stanley

Nile Stanley

University of North Florida, United States
GAB 2026 Speakers
Speaker at Addiction Medicine, Behavioral Health and Psychiatry 2026 - Andrew Drasen

Andrew Drasen

A Vision of Hope Media, United States
Speaker at Addiction Medicine, Behavioral Health and Psychiatry 2026 - Eric Cohen

Eric Cohen

Livio Labs, United States
Speaker at Addiction Medicine, Behavioral Health and Psychiatry 2026 - John Michael Weber

John Michael Weber

Open Door Mission in Houston Texas, United States
Speaker at Addiction Medicine, Behavioral Health and Psychiatry 2026 - Denis Larrivee

Denis Larrivee

University of Navarra, Spain
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