Substance dependence is deeply rooted in the brain's neuroanatomy, particularly involving the reward system, which includes the nucleus accumbens, prefrontal cortex, and ventral tegmental area. These structures regulate pleasure, motivation, and impulse control. Drugs like cocaine, opioids, and alcohol hijack this system by artificially increasing dopamine levels, reinforcing addictive behaviors. Over time, chronic use leads to structural and functional changes, such as reduced gray matter in the prefrontal cortex, impairing decision-making and self-regulation. Neuroplasticity plays a dual role in dependence and recovery, with targeted therapies focusing on rewiring these neural circuits to restore normal functioning.
Title : Integrating bibliopoetry therapy and digital health technologies for inflammation management: A neuropsychosomatic perspective
Nile Stanley, University of North Florida, United States
Title : Reduction of chronic neuropathic pain by a THC-CBD combination capsule: ongoing pilot study
Frederick J Goldstein, Philadelphia College of Osteopathic Medicine, United States
Title : Suicide prevention strategies for the law enforcement profession
Stephanie Schweitzer Dixon, SSD Consulting, United States
Title : The storm within: Neuropsychological insights into dysregulation and substance use in the adolescent brain
Ann Marie Leonard Zabel, Curry College, United States
Title : The three-second neuroshift™: Reset before relapse for addiction & emotional dysregulation
Edie Raether, NeuroShifts and Wings for Wishes Academy, United States
Title : TAMAR (Trauma, Addiction, Mental Health, and Recovery)
Angelo Reynolds, Transformers Academy, LLC, United States