Neurotransmitters such as dopamine, serotonin, and gamma-aminobutyric acid (GABA) play pivotal roles in addiction. Dopamine, often linked to the brain's reward system, is excessively released during substance use, reinforcing the behavior and creating a cycle of dependency. Serotonin dysregulation can lead to mood disturbances, increasing susceptibility to addiction. GABA, a neurotransmitter responsible for calming the brain, becomes imbalanced, leading to heightened anxiety and withdrawal symptoms. These disruptions alter neural pathways, making it challenging to break free from addiction. Recovery often focuses on restoring neurotransmitter balance through pharmacological interventions and behavioral therapies. Understanding the role of neurotransmitters sheds light on addiction's complexity, emphasizing the importance of tailored treatment strategies that address these biochemical changes for sustainable recovery.