Substance use rates are disproportionately higher in LGBTQ populations due to unique stressors like stigma, discrimination, and social exclusion. Substances are often used as coping mechanisms for dealing with minority stress and mental health issues such as anxiety and depression. Barriers to seeking treatment, including fear of discrimination in healthcare settings, further complicate recovery efforts. Tailored interventions that create safe and inclusive environments are essential. Peer support groups, culturally competent care, and affirming therapies can significantly improve outcomes. Addressing the intersectionality of identity and addiction ensures that treatment approaches resonate with the lived experiences of LGBTQ individuals.